The bacteria Mycobacterium tuberculosis, which causes the world's most infectious disease Tuberculosis (TB), can survive antibiotic treatment and live longer by changing their outer fat coating, ...
Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...
Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 6 (Mar. 13, 2001), pp. 3068-3073 (6 pages) Cytochrome P450 14α-sterol demethylases (CYP51) are essential ...
A research group is studying disease resistance in tuberculosis. The group has described the structure of a regulator that controls the expression of a pump that removes toxins from the bacteria.
AMES, Iowa – Edward Yu took note of the facts – nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally ...
Ting-Wan Lin, Melrose M. Melgar, Daniel Kurth, S. Joshua Swamidass, John Purdon, Teresa Tseng, Gabriela Gago, Pierre Baldi, Hugo Gramajo, Shiou-Chuan Tsai Proceedings of the National Academy of ...
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