Malaysian Prime Minister Anwar Ibrahim warned Wednesday that global trade is being weaponized as Southeast Asia’s foreign ministers opened an annual meeting while facing the looming threat of U.S. trade tariffs.

US President Donald Trump's letters on tariff increases are sending shivers through Southeast Asia. Malaysia will face a 25 percent tariff, one percent higher than the rate announced in April. The country has expressed concerns that unilateral measures could disrupt business activities that benefit both countries.

U.S. Secretary of State Marco Rubio will visit Malaysia this week for meetings of Southeast Asian Nations in his first trip to Asia as America's top diplomat, the State Department said on Monday, even as President Donald Trump announced hefty tariffs on the hosts and other regional partners and allies.