C. difficile infection - Symptoms and causes - Mayo Clinic
C. difficile infection that is severe and sudden can cause the colon to become inflamed and get larger, called toxic megacolon. And it can cause a condition called sepsis where the body's response to an …
C. diff: Facts for Clinicians | C. diff | CDC
Mar 5, 2024 · Patients with CDI exhibit clinical symptoms and test positive for the C. diff organism or its toxin. Colonization with C. diff is more common than infection. Colonized patients do not have …
The role of toxins in Clostridium difficile infection - PMC
The pathogenesis of C. difficile is primarily mediated by the actions of two large clostridial glucosylating toxins, toxin A (TcdA) and toxin B (TcdB). Some strains produce a third toxin, the binary toxin C. …
C. diff Infection: What It Is, Symptoms & Treatment
C. difficile releases toxins that damage the cells in your intestinal lining. This causes inflammation in your intestinal lining and colon (colitis). Whether you have symptoms, and how severe they are, will …
Clostridioides Difficile (C. diff) Toxins Test - UPMC
Sep 30, 2025 · C. diff is also common in older people who are in hospitals and nursing homes and in people who are getting chemotherapy for cancer. The C. diff toxins test looks at a stool sample to …
Study uncovers how the body's bile acids bind to block C ...
5 days ago · C. diff is a toxin-producing bacterium and the leading cause of health care-associated infections, causing serious infections in the gut and persistent diarrhea, abdominal pain, fever and ...
Clostridioides difficile infection - Wikipedia
Diagnosis is by stool culture or testing for the bacteria's DNA or toxins. [1] . If a person tests positive but has no symptoms, the condition is known as C. difficile colonization rather than an infection. [1] …